| IRAC Mode of Action | IRAC Group 5 Allosteric Activator |
|---|---|
| Active Ingredient | Spinosad |
| Length of Control | Fixed dose applications for 60 days residual control |
Transform your mosquito control offerings with Natular® DT, a professional larvicide tablet trusted in public health markets for over a decade, now being offered for pest management companies. Natular® DT is an easy-to-use, bi-layer tablet that prevents mosquito larvae from becoming flying, biting adults. The tablet’s two-layer design includes an effervescent layer that immediately releases the active ingredient Qalcova Spinosad into breeding habitats, quickly killing existing mosquito larvae, while the second layer releases slowly within the water column, providing 60 days of control.
By addressing mosquitoes in their immobile, larval stage, Natular® DT helps you deliver comprehensive mosquito management that addresses the entire lifecycle, offering customers a more effective solution than adult-only spray treatments, reducing callbacks and increasing customer satisfaction.
Natular® DT for non-public health pest management operations can be purchased with distributor Veseris.
Introduced in 2009, Clarke’s Natular® larvicide portfolio is like no other mosquito larvicide in the world. With formulations developed and manufactured exclusively by Clarke, its proprietary active ingredient, Qalcova Spinosad, is a product derived from a naturally occurring soil bacterium that provides the right balance of efficacy with environmental stewardship.
Spinosad was the first mosquito larvicide active ingredient registered under the EPA’s Reduced Risk program due to its reduced risk to human health and non-target organisms when compared to other available alternatives. Spinosad is of low acute and chronic toxicity to a wide range of non-target species, including mammals, birds, terrestrial wildlife, and fish.
Clarke earned the U.S. EPA Presidential Green Chemistry Challenge Award for the tablet technology it developed for use with Natular®. This prestigious award recognizes outstanding chemical technologies that incorporate the principles of green chemistry into chemical design, manufacturing and use, and that have been or can be utilized by industry in achieving their pollution prevention goals.
Spinosad in Soil
Spinosad degrades readily in the soil environment and is non-persistent. Exposure to sunlight accelerates the degradation process.
Spinosad in Water
By design, larvicides are intended to be applied to standing water sources to prevent mosquito breeding for a specific length of time. As an active ingredient, spinosad degrades rapidly in water, with exposure to sunlight, and presents a relatively low risk to beneficial and non-target insects when compared to other broad-spectrum insecticides. Under laboratory conditions, spinosad is toxic to some aquatic invertebrates, primarily upon chronic exposure. Fortunately, the rapid degradation of spinosad in natural aquatic environments prevents the long-term exposure that would be needed for these effects to occur in real-world situations.
Spinosad and Animals
When applied as indicated on the label for control of mosquito larvae, Natular® will not endanger human or animal health. Spinosad is not toxic to mammals. Spinosad is not carcinogenic, not genotoxic, and is not a reproductive or developmental toxin.
Spinosad and Pollinators
The EPA has determined that when liquid Natular® products are used according to label directions, they should not pose a significant risk to honey bees or pollinators. Spinosad in liquid form has been used extensively in more than 85 countries with over 250 registered crop uses since its first launch in agriculture without any reported adverse effects on bees. Granular and tablet formulations of Natular® will not pose a bee hazard given their application method.
What is the active ingredient in Natular® larvicides?
Spinosad. It is a naturally derived active ingredient produced during fermentation by the soil organism, Saccharopolyspora spinosa. The natural metabolites produced during the fermentation process were termed “spinosyns.” Spinosad is the collective term for the two most prominent and most active compounds in the fermentation broth (spinosyn A and spinosyn D). Hence the name “Spinosad.”
How is Natular®’s active ingredient, Spinosad, manufactured?
Spinosad is produced in a state-of-the-art fermentation facility in the United States, using natural feedstocks to maintain the fermentation process.
How does the active ingredient in Natular® formulations control mosquito larvae?
Spinosad has a novel mode of action; it alters the function of insect nicotinic acetylcholine receptors in a unique manner. Ultimately, paralysis sets in upon ingestion and contact, and the mosquito larvae don’t recover.
Are Natular® formulations suitable for use in organic agriculture?
Most formulations of Natular® registered for public health mosquito control with the US EPA are listed by the Organic Materials Review Institute (OMRI) for use in and around organic agriculture. Natular DT, which is designed to control mosquito breeding in containerized water sources, is not OMRI-listed, given its highly-targeted, contained use pattern.
Is Natular® a resistance management tool?
The active ingredient in Natular® products, spinosad, is the only active ingredient currently used for mosquito control that is designated by IRAC (Insect Resistance Action Committee) as Group 5. The benefit of this is that it has no cross-resistance with existing products, making Natular® an excellent option for resistance management.
